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Description
Previous studies of individuals affected by type 1 diabetes [37, 38] and AAb+ individuals [36] have revealed increased serum IGFBP1 levels

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Disruption of FR, whether functional or structural, can impair CNS folate availability and lead to developmental abnormalities or neurological dysfunction, with the clinical consequences depending on the timing, severity, and presumably on the individual genetic background

47 These tests can be used to assess baseline status, risk of complications, and response to treatment
