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However, it is noteworthy that ten oligonucleotide drugs have been officially approved by FDA as of January 2020 [55], which means that the technological obstacles for oligonucleotide therapeutics are being solved step by step and the development of oligonucleotide drugs targeting NNMT is still a promising method for the prevention or treatment of obesity and related T2D in the future

They essentially provide a structural scaffold while promoting cellular repair

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199 Another study showed that topical application of LL-37 encapsulated within PLGA nanoparticles accelerated wound closure, and re-epithelialization, besides enhanced granulation tissue formation at the wound bed