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These genes are involved in diverse metal toxicity tolerance (Table 2)

High total glutathione is associated with chemotherapy resistance (Traverso 2013), dyserythropoietic disorders (Kobayashi 2022), WBCs above 20x10(9)/L (which can falsely elevate glutathione levels by 25%), myelofibrosis, pyrimidine 5-nucleotidase deficiency, and riboflavin supplementation (Mayo Clinic)
