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doi: 10.1038/s41416-022-01747-0 120 TianSPengPLiJDengHZhanNZengZet al

Gastrointestinal dysfunctions in Parkinsons disease: symptoms and treatments

FIGURE 8 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 9) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors (258, 259)

Estimated doses between 0.045 mg/kg to 0.175 mg/kg and even greater than 0.175 mg/kg were associated with mild and severe effects respectively