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Clinical studies have demonstrated that supplementation with marine-derived PUFAs and antioxidants in VaMCI patients markedly elevated RvD1 levels in macrophages derived from peripheral blood mononuclear cells (PBMCs) [180, 181]

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doi: 10.1016/j.biomaterials.2022.121827 171 RussoAMaiolinoSPagliaraVUngaroFTatangeloFLeoneAet al

Conversely, in populations from Taiwan, Bangladesh, and Argentina, higher levels of MMA% and lower levels of DMA% have been linked to cancer and cardiovascular outcomes (Chen et al
