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People with gastrointestinal problems also run the risk of becoming B12 deficient as they are not able to absorb B12 from food

Int J Mol Sci 24:1161

If this internal ROS burst is blocked (as by high antioxidants or perhaps in certain metabolic states), Siglec-8-induced death might be less effective

Vet Clin Pathol 50:2027
