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Identification of C-met oncogene as a broadly expressed tumor-associated antigen recognized by cytotoxic T-lymphocytes
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And freezing, while it preserves the unreconstituted powder, destroys the reconstituted solution by forming ice crystals that shear peptide molecules apart
The histidine residue within the peptide sequence plays a critical role in coordinating the copper ion, forming a stable complex capable of interacting with biological molecules
