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In advanced liver disease, serum B12 levels can appear misleadingly normal or even elevated due to increased binding proteins and reduced clearance, despite actual tissue deficiency

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Most people in the general population can get enough vitamin B12 from a balanced diet

Inhibition of NNMT in adipose tissue led to smaller fat cells and reduced fat mass without affecting appetite or energy expenditure. Kraus et al., Cell Metabolism Enhanced Mitochondrial Energy and Endurance By increasing NAD, 5-Amino-1MQ supports mitochondrial function the energy engines of your cells
