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Description
Methods: In this preliminary, hypothesis-generating, prospective, double-blind, cross-over study, 16 patients with glaucoma or ocular hypertension and coexisting dry eye symptoms were randomized to receive either HA alone or HA + GSH-C4 for 4 weeks, separated by a 1-week washout

Raper SE, Wilson JM, Yudkoff M, Robinson MB, Ye X, Batshaw ML

Antonie Van Leeuwenhoek 111(1):526

Persistent nausea lasting more than 2 weeks after a dose increase warrants stepping back to the previous dose for 2 to 4 additional weeks before trying again
