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It is vital for protecting mitochondria, the energy centers of the cell

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Results from studies in recent decades have shown that bioactive compounds from plants have important roles in the prevention, and reducing the risks of chronic diseases, including cancer [258,259]

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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Thus, oxaloacetate from glucose contributes to NEAA pools by yielding aspartate and asparagine, connecting carbohydrate metabolism to nucleotide synthesis and adaptive stress responses

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