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It is vital for protecting mitochondria, the energy centers of the cell

Results from studies in recent decades have shown that bioactive compounds from plants have important roles in the prevention, and reducing the risks of chronic diseases, including cancer [258,259]
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

Thus, oxaloacetate from glucose contributes to NEAA pools by yielding aspartate and asparagine, connecting carbohydrate metabolism to nucleotide synthesis and adaptive stress responses
