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Although a plethora of macrophage phenotypes has been identified by the advent of single cell biology - amongst others resident macrophages, TNF + pro-inflammatory macrophages, IL1 + pro-inflammatory macrophages, Trem2 + macrophages, lipid-associated Trem2 hi-perilipin + macrophages, and IL10 + TNFAIP3 + macrophages (de Winther et al., 2023

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Sustained hyperoxia-induced NF-B activation improves survival and preserves lung development in neonatal mice

Studies also indicate EGCGs potential to reduce side effects of standard treatments while enhancing their therapeutic benefits through antioxidant and anti-inflammatory mechanisms