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These aged mice exhibited lower serum testosterone levels than young adult (3 months) mice (Figure 6B), indicating the presence of age-related testosterone secretion insufficiency

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The Wright and Harding 2015 review in the Journal of Alzheimers Disease situated the HGF/c-Met system more broadly as a candidate cognitive-research target, summarizing the receptors roles in neurogenesis, synaptic plasticity, and neuroprotection [4]
