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Finally, we note that as the samples were randomly assigned across the measurement batches in combination with samples from another independent study, balanced sample group representations for the present study could not always be ensured across the batches, which may have led to increased data variance

4.6 Liver and kidney functions and histopathological findings Approximately 30% of the LZD is excreted unchanged by the kidneys, while the rest is metabolized by oxidizing its morpholine ring, which is facilitated by ROS using NADPH in the liver (Wynalda et al., 2000), resulting in the creation of two metabolites: amino-ethoxy-acetic-acid and hydroxyethyl glycine (Nukui et al., 2013)

& Schweizer, U

10.1007/978-3-030-66014-7_1 54 KikuchiM.KashiiS.HondaY.TamuraY.KanedaK.AkaikeA