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Gut Microbes 3 , 279288 (2012)
When comparisons were made, all relevant treatment groups were included
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In SLC7A11 high cancer cells, high glutamate export results in a partial depletion of intracellular glutamate, which then drives cells through the relief of feedback inhibition to take up more glutamine as well as to activate glutaminase for glutamate replenishment, leading to glutamine dependency in SLC7A11 high cancer cells (Fig
