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Merkel M., Goebel B., Boll M., et al., Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2Mediated Ferroptosis, Antioxidants (Basel) 12, no
In contrast with the mouse and hamster, the rat, guinea pig and man are susceptible to the hepatotoxic effects of AFB 1 [34]

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Sirolimus has shown response rates of 80100% in adults with refractory AIH patients, while one pediatric study has reported a response rate of 50% [117,118,119]