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Reilly KM

PubMed: 40756949 URL: McGuire F, et al

Lepodisiran, an extended-duration short interfering RNA targeting lipoprotein(a): a randomized dose-ascending clinical trial

45 Although the role of each individual ROS cannot be investigated in vivo in humans, and, although superoxide anion and ONOO are the best characterized ROS, the possible role of other oxidant compounds such as hydrogen peroxide (the dismutation product of superoxide anions) and hypochlorous acid, which cannot be considered as free radicals but have a powerful oxidizing capacity, also needs to be mentioned