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Dysregulated trafficking (e.g., reduced ACSL4 transport to the ER) modulates PUFA esterification and peroxidation risk (109)

In contrast, patients with stiff-person syndrome predominantly recognize linear epitopes in all three domains on GAD65 and GAD67 (28), and specifically in the first 100aa, which constitute the regulatory sequence in the N-terminal GAD65 domain that is not recognized by the diabetes mellitus sera (61)

Decreases discomfort to the joints
