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In fact, in a toxicity study in Sprague-Dawley rats conducted with a single dose of 20 mg/kg (intramuscular, i.m.) of pentadecapeptide, no deaths or obvious abnormalities in body weight, food intake, or behavior were reported

However, due to the long term nature of the many studies and age of participants, it is unclear if this shift was due to age or contraceptive method

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