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eligibility typically requires a BMI of 35 kg/m or above (or 30 kg/m or above in certain ethnic groups), though thresholds vary by ICB Bariatric surgery referral for eligible patients, typically those with a BMI of 40 kg/m or above, or 35 kg/m or above with significant obesity-related comorbidities, in line with NICE guideline CG189 Structured diabetes prevention programmes for those at risk of type 2 diabetes These pathways offer genuine, monitored, and legally sanctioned routes to improved metabolic health

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For example, magnetic resonance imaging (MRI) devices are specifically contemplated within the scope of the embodiments, wherein the MRI devices (for example, 3 Tesla MRI devices) are capable of evaluating Meniere Disease progression and subsequent treatment with the pharmaceutical formulations disclosed herein