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Search Strategy A comprehensive search of PubMed/MEDLINE and the Cochrane Central Register of Controlled Trials (CENTRAL) was performed from database inception through the final search date
Moreover, indications of oxidative stress were detected in the frontal cortex, implying its early implication in ALS pathology 112
JAMA 281 : 21132118
Inhibition of this pathway under normal conditions phenocopied a hyperglycemic state by enhancing chemotherapeutic efficacy in mouse PDAC, while rescuing the pathway under high glucose abrogated the anti-tumor effects observed with chemotherapy
