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The prolonged increase in mitochondrial biogenesis could, in principle, cause an increase in the production of ROS, since mitochondrial electron transport chain was the main producer of ROS in most cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Andreadou I., Schulz R., Papapetropoulos A., Turan B., Ytrehus K., Ferdinandy P., Daiber A., Di Lisa F

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