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This combined evidence suggests that phosphorylation of Tau is part of an immune response toward a broad range of pathogens or their toxins, similar to A, both of which are diverted from their normal roles in neuronal homeostasis

It does not distinguish between analogues of active B12

The collective stability from all of these iondipole interactions can be substantially greater than that of the ionion interactions in an ionic compound, thus making the mixture more favored (more stable)