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In particular, Arginine 130 is here shown to be essential for catalysis in analogy with other MAPEGs

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Among the more than 20 identified aflatoxins, AFB 1 is the most toxic and has been classified as Group I carcinogen by the International Agency for Research on Cancer (IARC), due to its hepatoxicity, nephrotoxicity, immunotoxicity, teratogenicity, and mutagenicity [3,4,5,6]
