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Stress is one of significant factors that negatively affect fish growth and immune function

Importantly, these phase-dependent metabolic responses do not occur in isolation but are modulated by interacting physiological systems, including inflammation, the gut microbiota, circadian rhythms, physical activity, and behavioral factors [9,10,11,12,13,14]
The rapid accumulation in the large intestine highlights the possible importance of ET in the body to warrant such a response

The blind loop syndrome may produce deficiency of vitamin B 12 or folate