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With advancements in microbiome research, gut microbiota have been identified as pivotal regulators of host metabolism and immunity, modulating host redox homeostasis through metabolite secretion, epithelial barrier repair, and immunomodulation [6,7,8]

Oncogene (2026)

N Engl J Med 362(4):329344

18 The cost of new infections was included in the cost input for the model based on average prices reported for the treatment of ICU-emergent bloodstream infections
