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It is reported that treatment of CRC cells with luteolin, a naturally occurring flavonoid which is an agonist of PPAR, increased mRNA and protein expression of OCTN2 in a time- and dose-dependent manner, enhancing the intracellular accumulation of oxaliplatin (Qu et al., 2014)

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CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12

It reduces declines in mental abilities resulting from Alzheimer's disease and other neurodegenerative diseases