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This set of enzymes is located in the ER and the main player is the ethanol-inducible cytochrome P450 2E1 (CYP2E1), which converts ethanol to acetaldehyde, generating ROS [140,141]

4 This effect can be reversed with the administration (pharmacologically or nutritionally) of vitamin K 1 , which is also called phytonadione

KLOW is the broader stack for studying coordinated repair, matrix remodeling, and anti-inflammatory pathways together

It has been observed that many transcripts involved in amino acid metabolism are regulated during iron deficiency and that most of the amino acids affected include an iron-dependent step in their synthesis [82]