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55 Proposed mechanisms include suppression of the JAK-STAT pathway, downregulation of receptor expression, impaired post-receptor signaling, decreased histone deacetylase 5 activity in the hypothalamus, elevated C-reactive protein, endoplasmic reticulum stress, and hypothalamic inflammation

Urinary iodine concentrations in pregnant women and offspring brain morphology

The chance of full recovery has been estimated to be only 5% (28) as most patients do not regain their full pre-ME/CFS function

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