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Some studies suggest that APS can improve the permeability of the blood-brain barrier, enhancing its distribution in the brain (Jia et al., 2022), and providing a potential advantage for its application in neurological diseases
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A randomized double-blind phase III trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD/Doxil/Caelyx) in combination versus PLD in participants with platinum-resistant ovarian cancer (PROCEED) ( NCT01170650) Gynecol
2018;25(11):3021-3035 e3025
