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Once activated platelets release from their granules, growth factors with a capital role in tissue hemostasis and repair such as CTGF (conjunctive tissue growing factor), EGF (epidermal growing factor), FGF2 (fibroblast growing factor), FGF9, IGF-1 (insulin growing factor), PDGF- (platelet-derived growing factor), PDGF , PDGF , TGF (transforming growing factor), TGF1, TGF2, and VEGF (vascular endothelial growing factor)

doi:10.2147/MDER.S50594 AHA

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MT-I and MT-II have various modifications compared to -MSH, affecting their affinity to the various MCRs and, thus, their potential effects