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The high-affinity NMDA-Rs on the beta cell are already saturated at physiological glutamate concentrations in the islet, and are mainly activated through depolarization of beta cells [121]

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Use of Cu chelators and Cu ionophores have yielded encouraging anticancer activities in many preclinical models

Peptides can interact with this system in various ways, potentially promoting neuronal health, optimizing neurotransmitter activity, and supporting overall cognitive function