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RNA expression profiling also showed a significant increase in CDKN1A (p21), a p53 target gene coding for a cell cycle inhibitor, together with a decrease in the transcription of CCND1 , CCNE1 and Myc
that are present in the gut, convert tyrosine and phenylalanine to p -cresol for which the metabolic detoxication in humans is, as for APAP, predominantly via sulfation
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
10.1016/j.eururo.2014.07.010 [DOI] [PubMed] [Google Scholar] Ochiya T., Takenaga K., Asagiri M., Nakano K., Satoh H., Watanabe T., et al
