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Of note, intra-abdominal hypertension is quite frequent in critically ill patients and the cause of multiorgan dysfunction (Schachtrupp et al., 2007) (here, 25, 30, 40, and 50 mm Hg by intraperitoneal insufflation of ordinary air controlled and maintained by a manual manometer leads to invariable abdominal compartment syndrome), correlate fairly well with the circumstances in humans
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AMPK-mediated BECN1 phosphorylation promotes ferroptosis by directly blocking system Xc(-) activity