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The process is not unlike how yeast helps bread dough rise: It breaks down flour into its component sugars, gobbles the sugar, and releases carbon dioxide and ethyl alcohol into bubbles in the dough

really brings into question whether or not Complex I or Odh and to a lesser extent Pdh are the major ROS producing sites in mitochondria (Quinlan et al., 2014)

-oxidation, catalyzed by CYP4 enzymes, introduces a hydroxyl group at the terminal methyl group, which is subsequently oxidized to a carboxyl group, creating a dicarboxylic acid that is more readily excreted