melanotic sarcoma is also known as What Sarcoma? Melanoma - Wikipedia
Description
By inhibiting autophagy and inducing mitochondrial ROS, TMAO activates NLRP3 inflammasome, leading to the release and pyroptosis of IL-1/IL-18 dependent on caspase-1 in colon epithelium, which is a hallmark of IBD severity
PMID 15717057
Chronic inflammation can perpetuate this cycle, making an initial, temporary problem a chronic condition
Neurons depend on PLIN4 to facilitate the utilization of LDs by mitochondria for -oxidation during periods of inflammation and oxidative stress [46, 47]
