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The NHS guidance on vitamin B12 deficiency treatment recommends a loading course of injections first, followed by regular maintenance doses
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For example, mono- and tri-methylation at lysine 4 of histone H3 (H3K4me1 and H3K4me3) are associated with transcriptional activation, whereas tri-methylation at lysine 9 and lysine 27 of histone H3 (H3K9me3 and H3K27me3) correlate with transcriptional repression
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