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It should be, however, noted that there is a general lack of the studies that would demonstrate, for instance, the healing effect of disease-modifying drugs (DMDs) on the severely injured muscles and severely injured nerves

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The key factors involved in the inflammatory cascade during ulcerative colitis are cytokines, such as tumor necrosis factor- (TNF-), interferon- (IFN-), interleukin (IL) -2, IL-6, IL-8, which are also linked to chemokines and adhesion molecules [89,90]