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Vascular endothelium structure and physiological function The vascular endothelium is the innermost layer of the heart lumen, arteries, veins, and lymphatics and is composed of a single layer of vascular endothelial cells

Elevated nitric oxide (NO), reactive oxygen species (ROS), and pro-inflammatory cytokines (IL-1, TNF-, IFN-) further inhibit SLC7A11 and destabilize GPX4 activity in cancer cells

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Hypertension In medical terminology, high blood pressure and hypertension refer to the same condition: blood pressure that is persistently elevated