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Tramadol is a prescription opioid that is not used for opioid withdrawal

Given that glutamate is the major excitatory neurotransmitter in the central nervous system and NMDARs play critical roles in synaptic activity, it is not surprising that maladaptive NMDAR signaling is implicated in a broad range of neuropsychiatric, neurodevelopmental, and neurodegenerative disorders [6]
The effects of vitamin B12 supplementation in pregnancy and postpartum on growth and neurodevelopment in early childhood: Study Protocol for a Randomized Placebo Controlled Trial

Vitamin B12 injections are safe for most people but are not recommended for those with certain medical conditions, such as Lebers disease, without consulting a healthcare provider
