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Of interest, the down-expression of ACC2 results from an epigenetic process linked to histone deacetylation at the ACACB promoter by Sirtuin 1/6 that are activated by high cytosolic NAD + levels associated with enhanced FAO and reduced glucose metabolism
doi: 10.1038/s41580-019-0190-7 21
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Eur J Appl Physiol Occup Physiol 1985;54:131-5
