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Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK et al

SIRT2, present both in nuclear and cytoplasmic compartments, can increase MFN2 and decrease DRP1, thus promoting mitochondrial fusion 104,105

The authors proposed that chronic acetaminophen use may have generated glutathione deficiency and that this was in some way responsible for overproduction of 5-oxoproline
