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The compound also shows no inhibitory activity against nicotinamide phosphoribosyltransferase (NAMPT) or sirtuin 1 (SIRT1), key enzymes in the NAD+ salvage pathway

This selectivity, combined with its ability to efficiently cross cellular membranes, makes it an invaluable research tool for dissecting the specific contributions of NNMT to metabolic regulation

Dubaj C, Czyz K, Furmaga-Jablonska W
What is the tesamorelin compounding status