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Lightheadedness has been reported occasionally, potentially related to the vasodilatory effects of some components

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Kidney Health Issues : Chronic dehydration can lead to urinary tract infections, kidney stones, and even kidney failure

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Given the negligible concentration of labile copper in the cytosol, ATP7A and ATP7B require transfer of copper by a copper chaperone that can bind the metal in the cytosolic compartment and then deliver it to the secretory pathway, where these proteins are localized

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For most older adults with mild-to-moderate deficiency, no, high-dose oral or sublingual B12 corrects deficiency as well as injections in randomized trials

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