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The findings of this study indicate that the treatment of vitamin B12 deficiency can serve as a preventive measure against dementia and strokes.

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Studies using longitudinal muscle-myenteric plexus (LMMP) preparations isolated from TLR2/ mice in an organ culture system demonstrated that deficiency in TLR2which primarily recognizes lipoteichoic acid (LTA)led to reduced enteric neuronal density, accompanied by neuromuscular dysfunction, and increased morbidity and mortality during inflammatory challenge

Guidelines for the diagnosis and treatment of cobalamin and folate disorders British Society for Haematology