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doi: 10.1016/0003-2697(80)90139-6

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The kinetic parameters were determined in the presence of varying concentrations of tyrosine and DOPA from 0.1 to 5.5 mM and calculated by non-linear curve fitting using Origin8.0

KPV, the C-terminal tripeptide of -MSH (Lys-Pro-Val), has been investigated for its interaction with NF-B signaling, with researchers observing inhibition of NF-B nuclear translocation and downstream inflammatory cytokine expression (TNF-, IL-6, IL-8) in cell culture models