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The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person
Biomed Pharmacother 2022;145:112412
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Collectively, these findings implicate sustained dysregulation of CCK within the mPFC as a mechanistic substrate of stress-induced anxiety susceptibility in ASD
