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In nearly all cells, the main task of PPP is to provide ribose-5-phosphate

Abbreviations ECM: Extracellular matrix HDF: Human dermal fibroblasts GR: Glutathione reductase GSH: Glutathione MMP: Matrix metalloproteinase MTT: 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide PBS: Phosphate buffered saline ROS: Reactive oxygen species SA- -gal: Senescence-associated -galactosidase UV: Ultraviolet

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