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The endocannabinoid system is known to be involved in various digestive disorders, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD)
A key mechanism involves the modulation of cytochrome P450 enzymes, such as CYP3A and CYP2E1, which play critical roles in xenobiotic metabolism
Clin Cancer Res (2016) 22:518995
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