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The formation of Hcy is caused by the O-methylation of levodopa which is catalyzed by the catechol-O-methyltransferase (COMT) [126]

Recently, evidence has emerged linking the absence of the osteocalcin gene with metabolic dysfunctions such as hyperglycemia, glucose intolerance, increased fat mass and serum triglyceride levels, and decreased production of cells, insulin secretion, and adiponectin expression
BMC Complementary Medicine and Therapies , 22 , 116

39 The PDI value indicates the size of the sample heterogeneity, which can be monodispersed or polydispersed