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J Clin sleep medicine: JCSM: Off Publ Am Acad Sleep Med

of Molecular Embryology, Albert-Ludwigs-University Freiburg for preparing figures for this review

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Key Research Highlights: IGF-1-driven fibroblast proliferation and collagen synthesis documented Accelerated wound closure in animal models following GH secretagogue administration PI3K-Akt pathway activation identified as key mediator of IGF-1 tissue repair effects Direct blend wound healing studies limited